Creatine Kinase Mb Normal Range U L
Creatine kinase mb enzopak last update 04 2014 single step method reagent kit for quantitative estimation of creatine kinase mb activity in serum.
Creatine kinase mb normal range u l. Normal ranges of creatine kinase are as follows. Creatine kinase ck is a dimer of two non identical subunits b m. Creatine kinase is an enzyme found in the heart brain skeletal muscle and other tissues. For males normal levels of creatine kinase range between 38 to 174 units per liter u l of blood.
The isoenzymes are ck mm ck bb and ck mb. Physiologically when muscle contracts atp is converted to adenosine diphosphate adp and ck catalyzes the rephosphorylation of adp to atp using creatine phosphate as the phosphorylation reservoir. A significant concentration of ck mb isoenzyme is found almost exclusively in the myocardium and the appearance of elevated ck mb levels in serum is highly specific and sensitive for myocardial cell wall injury. Creatine kinase ck is an enzyme found primarily in the brain skeletal muscles and heart.
Ck levels are around 70 higher in healthy african americans compared to people of european descent. The ck enzyme is a dimer composed of subunits derived from. Conditions that cause damage to any of these three areas produce an elevated level of ck. The upper normal limit for men is anywhere from 200 to 395 u l 3 4 6 8 ukat l and for women it s up to 207 u l 3 52 ukat l 3 4 5.
Normal reference values for serum ck mb range from 3 to 5 percentage of total ck or 5 to 25 iu l. Background synopsis.