Epithelioid Mesothelioma Histology

Symptoms include shortness of breath and weight loss.

Epithelioid mesothelioma histology. Epithelial cells are prevalent in the human body but can be irritated by asbestos. Mutations in mesothelial cells caused by asbestos exposure create these variations. The epithelial cell type is identified by the clumping of cells and a square or cubic appearance. The cells are slow to metastasize or spread and respond more favorably to treatment than other mesothelioma cancer cells.

Another subset of this field called histopathology looks specifically at the microstructure of diseased cells and tissues which is what a pathologist will focus on when studying a tissue sample to make a diagnosis. Mesothelioma histology is the study of the function and structure of anatomy including tissues and cells. Upon entering the body these asbestos fibers can lodge into cells along the mesothelium which lines the lungs abdomen and heart. Asbestos exposure can mutate epithelial cells which then become cancerous.

This process is part of mesothelioma pathology which involves examining either tissue or fluid to determine if this cancer exists in the body. Papillary fragments and cohesive cell clusters moderate amount of cytoplasm round to ovoid nuclei prominent nuclei. Epithelioid mesothelioma cells have some notable characteristics. Epithelioid cell type this form of mesothelioma is the result of healthy epithelial cells in your body mutating into cancerous cells.

This form of mesothelioma is comprised of cells which resemble the normal mesothelial cells in that they are arranged in a trabecular fashion. Mesothelioma can be categorized histologically as epithelioid type sarcomatoid type biphasic type desmoplastic type among others. It can take many forms. Mesothelioma histology or mesothelioma histopathology is the study of tissue for the presence of mesothelioma.

Treatment and prognosis are affected by a patient s mesothelioma cell type. Ayesha azam for case of the week 476 ck5 6. They are square shaped cells and have visible nuclei plural for nucleus the center of the cell which carries genetic material. The three major mesothelioma cell types are epithelioid sarcomatoid and biphasic.

Epithelial cells can develop in the lining of the lungs abdomen or heart. The medical term histology refers to the microscopic study of tissue. Epithelioid mesothelioma is the most common mesothelioma cell type accounting for 50 to 70 of cases. The epithelial mesothelioma cell type makes up more than 50 of all cases.

Consequently there are many diseases to be differentiated when the diagnosis of mesothelioma is based on histological analyses.