Mesothelioma Vs Adenocarcinoma Cytology

The distinction between adenocarcinoma and malignant mesothelioma in effusion cytology can be challenging.

Mesothelioma vs adenocarcinoma cytology. Conventional cytomorphologic assessment is the first step to establish an accurate diagnosis in pleural effusions. Several panel exists no agreed upon best panel. There were no false positive diagnoses of mm in effusion specimens during this time period. Mesothelioma and adenocarcinoma are both forms of cancer but are significantly different diseases.

Mesothelioma pathologists almost always request a tissue biopsy following a mesothelioma cytology report. Malignant mesothelioma and adenocarcinoma are two different forms of cancer that present similarly in patients and can be confused by cytopathologists. Furthermore you may get more reliable information about the cell type from a histology report rather than just a cytology report. Cea monoclonal and polyclonal.

However there is still a small risk of tumor cell seeding microscopic spreading of cancer due to cells moving during a biopsy during cytologic procedures. Adenocarcinoma is a subtype of non small cell lung cancer nsclc. In addition 6 cases were designated atypical 2 were misclassified as positive for adenocarcinoma 1 was suspicious for mesothelioma and the remainder were classified as benign. While cytologists are getting better at diagnosing mesothelioma there are still margins of error and misdiagnosis does occasionally occur.

Adenocarcinoma is a subtype of non small cell lung cancer and it usually starts in the glands in the lungs. Mesothelioma vs adenocarcinoma overview. Several cytologic features have predictive value to seperate malignant. Mesothelial proliferation versus 97 5 of malignant mesothe lioma and 92 5 of malignant mesothelioma versus 92 5 of adenocarcinoma.

They each have different causes and prognoses and require vastly different treatment approaches. Usually two carcinoma markers two mesothelial markers. Given the frequent overlap in their morphologic features and the imperfect sensitivity and specificity of any one marker for the distinction the diagnostic workup often requires immunohistochemical panels. They each have different causes and prognoses and require very different treatment approaches.

By forgoing a tissue biopsy there is less risk of morbidity of the patient.